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what is belviq lorcaserin 10 mg?

belviq lorcaserin 10 mg is a selective serotonin 2C (5-HT2C) receptor agonist that
reduces body weight. Given that 5-HT2C receptor expression is primarily limited to a few regions of the
central nervous system, lorcaserin was predicted to cause weight loss with few unintended
pharmacological effects.

belviq lorcaserin 10 mg
belviq lorcaserin 10 mg

Mechanism of Action :

The exact mechanism of belviq lorcaserin 10 mg is unknown. However, lorcaserin is believed to
decrease food consumption and promote satiety by selectively activating 5-HT2C
receptors on anorexigenic pro-opiomelanocortin neurons in the hypothalamus. At the
recommended daily dose, lorcaserin interacts selectively with 5-HT2C receptors (versus 5-
HT2A, 5-HT2B, other 5-HT receptor subtypes, 5-HT receptor transporter, and 5-HT


belviq lorcaserin 10 mg, used in combination with diet
and exercise, results in modest weight loss of
about 12.9 lb (5.8 kg) compared with 5.6 lb
(2.5 kg) with placebo.3
On average, about
47% of patients will lose at least 5% of their
body weight (about 11.1 lb [5 kg]) compared with 23% of patients receiving placebo
(number needed to treat [NNT] = 4).1-3
About 22% of patients will lose at least
10% of their body weight vs. 9% of patients
receiving placebo (NNT = 7). This weight
loss is maintained, on average, for two years.


Lorcaserin is well tolerated. In early studies, less than 1% of patients discontinued
treatment because of dizziness, and about
2% discontinued because of headache.2
premarketing studies, more patients discontinued lorcaserin than placebo because of
adverse effects,



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